1. Describe the steps in designing, delivering, and debriefing a translational simulation session and/or program. 2. Identify the human factors and cultural issues that impact safety and performance in specific healthcare environments. 3. Apply a translational simulation approach to planning new physical spaces and to clinical redesign of workflows and processes. 4. Analyse how simulation design, delivery, and debriefing can shape culture, values, and priorities for healthcare teams. 5. Lead learning conversations after translational simulation activities toward improvement efforts. 6. Examine how latent safety threats can be identified and explored through translational simulation. 7. Adapt principles of translational simulation design, delivery, and debriefing to a specific healthcare context.