BMED11-207: Medical and Molecular Genetics

Description

This subject introduces the basic concepts behind DNA structure, replication and gene expression, with an emphasis on human disease. Mechanisms of mutation and DNA repair will be examined and their consequences discussed. Case studies for specific genetic diseases will be employed to demonstrate single gene defects, complex multi-factorial diseases and chromosomal disorders. Clinical commentary on important disorders, including cystic fibrosis, achondroplasia, Fragile X, trisomy 21, etc. will be provided throughout the lecture series. More specialised topics including inborn errors of metabolism, mitochondrial disorders and the genetic basis of cancer and ageing will also be presented. Finally recent molecular advances in gene therapy and the Human Genome Project will be examined in relation to ethical, legal and social issues relevant to medical genetics. Students will also acquire standard laboratory techniques used in DNA diagnostic tests.

Subject details

Type: Undergraduate Subject
Code: BMED11-207
EFTSL: 0.125
Faculty: Faculty of Health Sciences and Medicine
Semesters offered:
  • January 2022 [Standard Offering]
  • January 2023 [Standard Offering]
Credit: 10
Study areas:
  • Health, Biomedical, and Sport Sciences
Subject fees:
  • Commencing in 2021: $3,890.00
  • Commencing in 2022: $3,950.00
  • Commencing in 2023: $4,050.00
  • Commencing in 2021: $5,260.00
  • Commencing in 2022: $5,260.00
  • Commencing in 2023: $5,400.00

Learning objectives

1. Describe the mechanisms relating to storage, replication and expression of genetic material. 2. Explain the relationship between chromosomal, single- and multifactorial-gene mutations and human disease. 3. Provide a comprehensive overview of mechanisms of DNA mutation and repair. 4. Describe methods of identifying human disease genes and treatment of genetic disorders. 5. Develop laboratory and analytical skills in the area of molecular genetics. 6. Discuss and debate the ethical, legal and social issues relevant to medical genetics. 7. Work competently in a group and share information in tutorials. 8. Develop a high level of communication skills, both written and orally.

Enrolment requirements

Requisites:

Nil
Assumed knowledge:

Assumed knowledge is the minimum level of knowledge of a subject area that students are assumed to have acquired through previous study. It is the responsibility of students to ensure they meet the assumed knowledge expectations of the subject. Students who do not possess this prior knowledge are strongly recommended against enrolling and do so at their own risk. No concessions will be made for students’ lack of prior knowledge.

Assumed Prior Learning (or equivalent):

Restrictions:

This subject is not available as a general elective. To be eligible for enrolment, the subject must be specified in the students’ program structure.

Subject outlines

Subject dates

  • Standard Offering
    Enrolment opens: 14/11/2021
    Semester start: 17/01/2022
    Subject start: 17/01/2022
    Cancellation 1: 31/01/2022
    Cancellation 2: 07/02/2022
    Last enrolment: 30/01/2022
    Withdraw - Financial: 12/02/2022
    Withdraw - Academic: 05/03/2022
    Teaching census: 11/02/2022
  • Standard Offering
    Enrolment opens: 13/11/2022
    Semester start: 16/01/2023
    Subject start: 16/01/2023
    Cancellation 1: 30/01/2023
    Cancellation 2: 06/02/2023
    Last enrolment: 29/01/2023
    Withdraw - Financial: 11/02/2023
    Withdraw - Academic: 04/03/2023
    Teaching census: 10/02/2023
Standard Offering
Enrolment opens: 14/11/2021
Semester start: 17/01/2022
Subject start: 17/01/2022
Cancellation 1: 31/01/2022
Cancellation 2: 07/02/2022
Last enrolment: 30/01/2022
Withdraw - Financial: 12/02/2022
Withdraw - Academic: 05/03/2022
Teaching census: 11/02/2022